发明名称 |
Method for detecting mutated alleles |
摘要 |
A method for detecting mutated alleles in an excess of wild type alleles in a sample by isolating sample DNA; amplifying a target DNA sequence; and separating mutated DNA sequences from wild type DNA sequences by virtue of the preferential binding of the wild type sequences to carrier-bound complementary oligonucleotides. The amplification and separation steps may be iterated through one or more additional cycles to enhance sensitivity.
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申请公布号 |
US6599704(B2) |
申请公布日期 |
2003.07.29 |
申请号 |
US20010849901 |
申请日期 |
2001.05.03 |
申请人 |
WAGENER CHRISTOPH |
发明人 |
WAGENER CHRISTOPH |
分类号 |
C12Q1/68;G01N27/447;G01N30/02;G01N30/46;(IPC1-7):C12Q1/68;C12Q1/70;C12N15/00;C12P19/34;B01D59/42 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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