发明名称 |
CARBOXAMIDE MODIFIED POLYAMINE CHELATORS AND RADIOACTIVE COMPLEXES THEREOF FOR CONJUGATION TO ANTIBODIES |
摘要 |
A group of functionalized polyaminocarboxamide modified chelators that form complexes with rare earth-type metal ions are disclosed. The complexes, covalently attached to an antibody or antibody fragment, can be used for therapeutic and/or diag- nostic purposes.
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申请公布号 |
CA2134092(C) |
申请公布日期 |
2003.07.29 |
申请号 |
CA19932134092 |
申请日期 |
1993.04.23 |
申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
KRUPER, WILLIAM J., JR.;FORDYCE, WILLIAM A.;SHERRY, A. DEAN |
分类号 |
C07D257/02;A61K39/44;A61K51/00;A61K51/04;A61K51/10;C07B59/00;C07F5/00;C07K16/00;C07K16/30;(IPC1-7):C07K16/00;A61K43/00;A61K49/00;C07D403/10;A61K47/48;G01N33/574;G01N33/577;G01N33/60 |
主分类号 |
C07D257/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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