发明名称 |
Growth hormone secretagogue related receptors and nucleic acids |
摘要 |
This invention relates to a new family of receptors, growth hormone secretagogue-related receptors, which exhibit moderate sequence identity to both the growth hormone secretagogue receptor (GHS-R) and the neurotensin receptor (NT-R). These newly identified receptors are expressed in a diverse set of tissues. This invention also relates to nucleic acids encoding these receptors, and to the use of these receptors to identify ligands that modulate growth hormone release as well as other modulators of endocrine function.
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申请公布号 |
US6599718(B1) |
申请公布日期 |
2003.07.29 |
申请号 |
US20010743742 |
申请日期 |
2001.03.15 |
申请人 |
MERCK & CO., INC. |
发明人 |
LIU QINGYUN;HOWARD ANDREW D.;MCKEE KAREN KULJU |
分类号 |
G01N33/50;A61K38/00;C07K14/705;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;C12Q1/02;G01N33/15;G01N33/566;(IPC1-7):C12N15/12;C12N15/63;C07K14/47 |
主分类号 |
G01N33/50 |
代理机构 |
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主权项 |
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地址 |
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