| 摘要 |
This invention provides (1R, 4aR, 8aR)- 1,2,3,4,5,6,7,8-perhydroisoquinolin-1-carbonyl-(L)-prolinyl-(L)- arginine aldehyde and pharmaceutically acceptable salts and solvates thereof, pharmaceutical formulations containing said compounds and methods of their use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents.
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