Adeno-associated virus and adenovirus chimeric recombinant viruses useful for the integration of foreign genetic information into the chromosomal dna of target cells

摘要

A chimeric viral vector comprising a functional packaging signal derived from a adenovirus linked to a nucleic acid sequence and flanked by adeno-associated virus-inverted terminal repeats (AAV-ITR) which is capable of infecting a cell and integrating DNA into the host genome.