发明名称 Diphenyl ether compounds that inhibit monoamine reuptake and are useful in treating or preventing sexual dysfunctions
摘要 A compound of general formula (I), or pharmaceutically acceptable salts, solvates or polymorphs thereof; wherein R3 is independently CF3, OCF3, C1-4alkylthio or C1-4alkoxy; n is 1, 2 or 3; and the other variables are as defined in the claims. These compounds inhibit monoamine re-uptake and in particular exhibit activity as selective serotonin re-uptake inhibitors, and are suitable for treating or preventing disorders such as depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder, substance abuse disorders and sexual dysfunction including premature ejaculation.
申请公布号 NZ519972(A) 申请公布日期 2003.07.25
申请号 NZ20010519972 申请日期 2001.03.19
申请人 PFIZER INC 发明人 ANDREWS, MARK DAVID;HEPWORTH, DAVID;MIDDLETON, DONALD STUART;STOBIE, ALAN
分类号 A61K31/137;A61K31/145;A61K31/165;A61K31/18;A61K31/195;A61K31/24;A61K31/277;A61K31/397;A61K31/40;A61K31/415;A61K31/4164;A61K31/4192;A61K31/4196;A61K31/5375;A61P15/00;A61P15/10;A61P25/00;A61P25/14;A61P25/24;A61P25/30;A61P43/00;C07C45/71;C07C47/55;C07C47/575;C07C205/44;C07C213/02;C07C213/08;C07C217/58;C07C217/90;C07C229/38;C07C237/28;C07C237/30;C07C255/43;C07C255/59;C07C303/38;C07C311/05;C07C311/08;C07C311/37;C07C317/32;C07C319/20;C07C323/20;C07C323/32;C07C323/67;C07D205/04;C07D207/12;C07D231/38;C07D233/61;C07D249/06;C07D249/08;C07D295/08;C07D295/096;C07D295/18;C07D295/192;C07D521/00 主分类号 A61K31/137
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