发明名称 |
CCR6 chemokine receptor disruptions, compositions and methods relating thereto |
摘要 |
The present invention relates to compositions and methods relating to the characterization and function of CCR6. Specifically, the present invention provides transgenic animals comprising disruptions in a CCR6 gene and methods of treating diseases conditions, such as pain, inflammatory bowel disease and rheumatoid arthritis. The present invention further relates to agents that modulate CCR6 and methods of screening for agents that modulate CCR6 for the treatment of diseases and conditions such as pain, inflammatory bowel disease and rheumatoid arthritis.
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申请公布号 |
US2003140361(A1) |
申请公布日期 |
2003.07.24 |
申请号 |
US20020254089 |
申请日期 |
2002.09.23 |
申请人 |
BRENNAN THOMAS J.;KIRK CHRISTOPHER J. |
发明人 |
BRENNAN THOMAS J.;KIRK CHRISTOPHER J. |
分类号 |
A01K67/027;C07K14/715;C12N5/02;C12N15/85;(IPC1-7):A01K67/027 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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