发明名称 |
Methods and dosage forms for improving the bioavailability of therapeutic agents |
摘要 |
The present invention relates to methods and dosage forms for improving the bioavailability of therapeutic agents that are metabolized in the upper gastrointestinal (GI) tract. The present invention improves the bioavailability of by administering such therapeutic agents in a floating dosage form. The floating dosage forms are kept in the stomach for extended periods of time and the therapeutic agents are not immediately released after ingestion. Controlled release of such therapeutic agents from the dosage forms prevents enzyme saturation thereby improving the bioavailability of such therapeutic agents.
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申请公布号 |
US2003138486(A1) |
申请公布日期 |
2003.07.24 |
申请号 |
US20020283520 |
申请日期 |
2002.10.29 |
申请人 |
KING PHARMACEUTICALS RESEARCH |
发明人 |
OUADJI LAURE PATRICIA NJIKI |
分类号 |
A61K9/00;A61K9/22;A61K9/48;A61P9/12;(IPC1-7):A61K9/46;A61K9/14 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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