USE OF SYNTHETIC INORGANIC NANOPARTICLES AS CARRIERS FOR OPHTHALMIC AND OTIC DRUGS
摘要
The use of nanoparticles of inorganic materials (e.g., synthetic smectite clays) in ophthalmic and otic pharmaceutical compositions is described. The nanoparticles are utilized as biologically inert carriers or depots for ophthalmic and otic drugs. The nanoparticles may also be utilized to modify the rheological properties of the compositions, so as to enhance the viscosity or flow characteristics of the compositions and/or increase the retention time of the compositions in the eye or ear.
申请公布号
WO03059194(A2)
申请公布日期
2003.07.24
申请号
WO2002US41248
申请日期
2002.12.20
申请人
ALCON, INC.;KETELSON, HOWARD, ALLEN;MEADOWS, DAVID, L.