摘要 |
<p>Compounds represented by the general formula (|) or pharmaceutically acceptable salts or solvates thereof: (|) [wherein R1 is C1-6 alkyl, C1-6 alkoxy, halogeno, amino, nitro, or hydroxyl; n is an integer; R2 is CO2R3, hydroxymethyl, or a nitrile group; and R3 is hydrogen, C1-6 alkyl, or aralkyl]. The use of the compounds makes it possible to produce phenylpiperidine derivatives having integrin αvβ3-inhibiting activity safely at a low cost by a relatively short reaction process.</p> |