发明名称 PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED-1,3-DIOXANE-4-YL) ACETIC ACID DERIVATES
摘要 <p>The invention relates to a process for the conversion of group X in a 2-6(-substituted)-1,3-dioxane-4yl) acetic acid derivative according to formula 2 into a group OY in the presence of a phase transfer catalyst and an oxylating agent, by using as a phase transfer catalyst a quarternary phosphonium ion and by using as an oxylating agent an OY ion. X stands for a halogen and R1 and R2 and R3 are each independently a C1-4 alkygroup or R1 and R2 together with the C-atom to which they are bound form a 5- or 6-membered cycloalkyl; Y stands for RA-CO- or for RB-SO2- with RA, RB are chosen from the group of alkyl or aryl with 1-12 C-atoms.</p>
申请公布号 WO2003059901(A1) 申请公布日期 2003.07.24
申请号 NL2002000876 申请日期 2002.12.09
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