| 发明名称 |
IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OF PSMA |
| 摘要 |
<p>The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express NAALADase and/or PSMA. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express NAALADase and/or PSMA to which the compounds of the invention have an affinity. In another embodiment, the invention relates to pharmaceutical compositions containing urea compounds.</p> |
| 申请公布号 |
WO03060523(A1) |
申请公布日期 |
2003.07.24 |
| 申请号 |
WO2003US00680 |
申请日期 |
2003.01.10 |
| 申请人 |
JOHNS HOPKINS UNIVERSITY;POMPER, MARTIN, G.;ZHANG, JIAZONG;KOZIKOWSKI, ALAN, P.;MUSACHIO, JOHN, L. |
发明人 |
POMPER, MARTIN, G.;ZHANG, JIAZONG;KOZIKOWSKI, ALAN, P.;MUSACHIO, JOHN, L. |
| 分类号 |
A61P35/00;C07C275/24;C07C323/59;C12Q1/37;G01N33/50;G01N33/60;G01N33/62;G01N33/68;(IPC1-7):G01N33/60;C07C275/16;A61K31/17 |
主分类号 |
A61P35/00 |
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