发明名称 |
Plasmodium falciparum AMA-1 protein and uses thereof |
摘要 |
In this application is described the expression and purification of a recombinant Plasmodium falciparum (3D7) AMA-1 ectodomain. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant AMA-1 is useful as a diagnostic reagent, for use in antibody production, and as a protein for use alone, or as part of, a vaccine to prevent malaria.
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申请公布号 |
US2003138450(A1) |
申请公布日期 |
2003.07.24 |
申请号 |
US20020271145 |
申请日期 |
2002.10.15 |
申请人 |
LANAR DAVID E.;DUTTA SHEETIJ;WARE LISA A.;NAIR LALITHA P.V. |
发明人 |
LANAR DAVID E.;DUTTA SHEETIJ;WARE LISA A.;NAIR LALITHA P.V. |
分类号 |
A61K39/00;C07K14/445;(IPC1-7):A61K39/002;C07H21/04;C12N1/10;C12N15/74 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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