| 摘要 |
<p>An amino alcohol derivative or phosphonic acid derivative each having excellent immunosuppressive activity; a pharmacologically acceptable salt thereof or pharmacologically acceptable ester thereof; and a medicinal composition containing any of these. (I) (In the formula, R1 and R2 each represents hydrogen or an amino-protecting group; R3 represents hydrogen or a hydroxy-protecting group; R4 represents lower alkyl; n is an integer of 1 to 6; X represents oxygen or nitrogen optionally substituted by lower alkyl, etc.; Y represents ethylene; Z represents C1-10 alkylene; R5 represents aryl or substituted aryl; and R6 and R7 each represents hydrogen; provided that when R5 is hydrogen, then Z is neither a single bond nor linear C1-10 alkylene.)</p> |
