| 发明名称 |
Method for identifying an enzyme to design anti-cancer compounds |
| 摘要 |
The present invention relates to a method for identification of enzymes that are preferentially expressed in certain tumor tissue as compared with rapidly growing normal cells or tissue, use of said enzymes for the compound design to generate an active anti-cancer substance selectively in tumor tissue, compounds designed based on said enzymes, their pharmaceutically acceptable salts as well as pharmaceutical composition thereof.
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| 申请公布号 |
US2003138864(A1) |
申请公布日期 |
2003.07.24 |
| 申请号 |
US20020301460 |
申请日期 |
2002.11.21 |
| 申请人 |
ISHITSUKA HIDEO;OKABE HISAFUMI;SHIMMA NOBUO;TSUKUDA TAKUO;UMEDA ISAO |
发明人 |
ISHITSUKA HIDEO;OKABE HISAFUMI;SHIMMA NOBUO;TSUKUDA TAKUO;UMEDA ISAO |
| 分类号 |
G01N33/50;A61K31/337;A61K31/401;A61K31/426;A61K31/4725;A61K31/4745;A61K31/506;A61K31/517;A61K31/519;A61K31/53;A61K31/5377;A61K31/704;A61K31/7068;A61K31/7076;A61K38/00;A61K47/48;A61P35/00;A61P43/00;C07K5/06;C07K7/06;C12N15/09;C12Q1/02;C12Q1/26;C12Q1/32;C12Q1/37;C12Q1/48;C12Q1/68;G01N33/15;G01N33/573;G01N33/574;G01N37/00;(IPC1-7):G01N33/574;A61K31/707;A61K31/513;A61K31/474;C07H19/048;C07D498/14;C0745/02;C0735/14 |
主分类号 |
G01N33/50 |
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