发明名称 |
Total internal reflection fluorescence microscope having a conventional white-light source |
摘要 |
A microscope for use in total internal reflection fluorescence microscopy (TIRFM) is provided. The microscope includes a first white-light source for directing light along a first optical path; an annular slit member disposed in the first optical path, the annular slit member having an annular slit for blocking all but an annulus of light corresponding to the annular slit; and an objective lens for directing the annulus of light to a specimen such that TIRFM of the specimen is achieved. Also provided are various ways for converting the microscope to and from a TIRFM microscope and a conventional microscope.
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申请公布号 |
US6597499(B2) |
申请公布日期 |
2003.07.22 |
申请号 |
US20010769072 |
申请日期 |
2001.01.25 |
申请人 |
OLYMPUS OPTICAL CO., LTD. |
发明人 |
KAWANO YOSHIRO;ABE CHIKARA;ABE KATSUYUKI;TAMURA KEISUKE |
分类号 |
G01N21/64;G02B21/06;G02B21/10;G02B21/16;(IPC1-7):G02B21/06 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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