| 发明名称 |
Inhibitors of alpha4beta1 mediated cell adhesion |
| 摘要 |
The present invention relates to small molecules according to the formula [I]:which are potent inhibitors of alpha4beta1 mediated adhesion to either VCAM or CS-1 and which can be used for treating or preventing alpha4beta1 adhesion mediated conditions in a mammal such as a human.
|
| 申请公布号 |
US6596752(B1) |
申请公布日期 |
2003.07.22 |
| 申请号 |
US20020193137 |
申请日期 |
2002.07.12 |
| 申请人 |
TANABE SEIYAKU CO., LTD.;PHARMACIA & UPJOHN COMPANY |
发明人 |
LOBL THOMAS J.;TEEGARDEN BRADLEY R.;POLINSKY ALEXANDER;RISHTON GILBERT M.;YAMAGISHI MASAFUMI;TANIS STEVEN;FISHER JED F.;THOMAS EDWARD W.;CHRUSCIEL ROBERT A. |
| 分类号 |
C07D295/18;A61K31/198;A61K31/223;C07C229/46;C07C233/60;C07C233/63;C07C233/81;C07C233/83;C07C233/87;C07C235/40;C07C235/64;C07C235/84;C07C237/22;C07C237/40;C07C237/42;C07C255/29;C07C255/46;C07C259/08;C07C271/22;C07C271/28;C07C275/26;C07C275/42;C07C311/21;C07C311/64;C07D207/16;C07D209/20;C07D209/22;C07D213/64;C07D213/81;C07D213/82;C07D217/26;C07D233/24;C07D233/54;C07D233/64;C07D295/185;C07D295/192;C07D307/68;C07D333/24;(IPC1-7):A61K31/415;A61K31/535;A61K31/47;A61K31/44;A61K31/40 |
主分类号 |
C07D295/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
