发明名称 |
Notkun beta mótlyfjum vithtaka GAL3 til thess ath methhöndla depru og/etha kvítha og efnasambönd sem eru nytsöm vith athferthirnar |
摘要 |
This invention is directed to pyrimidine and indolone derivatives which are selective antagonists for the GAL3 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety. This invention also provides a method of treating depression and/or anxiety in a subject which comprises administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist. |
申请公布号 |
IS6880(A) |
申请公布日期 |
2003.07.21 |
申请号 |
IS20030006880 |
申请日期 |
2003.07.21 |
申请人 |
H. LUNDBECK A/S |
发明人 |
TOMAS P. BLACKBURN;LAKMAN W. BOTEJU;JOHN M. WETZEL;HEIDI CHEN;BHARAT LAGU;STEWART NOBLE;MICHEAL KONKEL;IAN JAMIE TALISMAN;MATHIVANAN PACKIARAJAN;HERMO JIMENZ;KITAE LIM |
分类号 |
C07D239/50;A61K;A61K31/40;A61K31/404;A61K31/415;A61K31/416;A61K31/42;A61K31/422;A61K31/425;A61K31/44;A61K31/4439;A61K31/47;A61K31/4709;A61K31/495;A61K31/50;A61K31/505;A61K31/506;A61K31/535;A61K31/5377;A61P25/00;A61P25/22;A61P25/24;A61P43/00;C07D;C07D209/02;C07D209/40;C07D209/48;C07D209/82;C07D215/38;C07D231/56;C07D239/02;C07D239/42;C07D261/06;C07D401/00;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/02;C07D403/04;C07D403/12;C07D405/00;C07D405/12;C07D405/14;C07D409/04;C07D409/06;C07D409/12;C07D409/14;C07D413/00;C07D413/04;C07D413/06;C07D417/00;C07D417/12 |
主分类号 |
C07D239/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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