发明名称 COMPOSITION COMPRISING A TRAMADOL MATERIAL AND A SELECTIVE COX-2 INHIBITOR DRUG.
摘要 <p>This invention relates to a pharmaceutical composition comprising a combination of a tramadol material and a selective COX-2 inhibitor drug and use for treating or preventing pain, inflammation and certain neurological disorders and cancers. The compositions have a synergistic effect, use less of each ingredient and have less opioid side effects such as abuse liability, tolerance, constipation and respiratory depression.</p>
申请公布号 MXPA01008903(A) 申请公布日期 2003.07.21
申请号 MX2001PA08903 申请日期 2000.02.29
申请人 JOHNSON & JONHSON. 发明人 CODD, ELLEN, E.
分类号 A61K31/365;A61K31/415;A61K31/42;A61K45/06;A61P19/10;A61P25/02;A61P29/00;A61P35/00;(IPC1-7):A61K31/135;A61P19/02;A61P25/04;A61P25/06;A61P25/28 主分类号 A61K31/365
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