| 摘要 |
<p>The invention concerns a biocompatible microparticle designed to be inhaled comprising at least an active principle and at least a layer coating said active particle which is the outer layer of said microparticle, said outer layer comprising at least a coating agent. The invention is characterised in that said microparticle has a mean diameter ranging between 1 mu m and 30 mu m, an apparent density ranging between 0.02 g/cm<3> and 0.8 g/cm<3> and it is obtainable by a method comprising essential steps which consist in bringing together a coating agent and an active principle and introducing a supercritical fluid, under agitation in a closed reactor.</p> |
