发明名称 NEW IMIDAZOLE DERIVATIVE, METHOD FOR PRODUCING THE SAME AND USE OF THE SAME
摘要 PROBLEM TO BE SOLVED: To provide a compound having a steroid C17, 20 lyase inhibitory activity, and useful as a preventing and treating agent of a tumor such as prostatism, breast cancer, etc., and a method for separating an optically active form of the compound from a mixture of optical isomers in a good efficiency. SOLUTION: This compound expressed by formula (1) (wherein, each of the marks has the same meaning as defined in the specification), its salt or its prodrug are provided and the method for obtaining the optical isomer is provided by performing an optical resolution of the mixture of the optical isomers by using an optical resolution agent such as a tartranilic acid, etc. COPYRIGHT: (C)2003,JPO
申请公布号 JP2003201282(A) 申请公布日期 2003.07.18
申请号 JP20010351035 申请日期 2001.11.16
申请人 TAKEDA CHEM IND LTD 发明人 TASAKA AKIHIRO;TOBITAKA TAKENORI;MATSUNAGA NOBUYUKI;KUSAKA MASAMI;ADACHI MARI;AOKI ISAO;OJIDA AKIO
分类号 C07D233/62;A61K31/165;A61K31/4174;A61K31/4188;A61K31/437;A61K45/00;A61P5/28;A61P35/00;A61P43/00;C07D233/54;C07D471/04;C07D487/04;(IPC1-7):C07D233/62;A61K31/417;A61K31/418 主分类号 C07D233/62
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