| 发明名称 |
SUBSTITUTED AMINO CARBOXAMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE |
| 摘要 |
The present invention relates to compounds of formula (I) useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the betasecretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharamaceutical compositions and methods of treatment to reduce A beta peptide formation.
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| 申请公布号 |
CA2472617(A1) |
申请公布日期 |
2003.07.17 |
| 申请号 |
CA20032472617 |
申请日期 |
2003.01.06 |
| 申请人 |
ELAN PHARMACEUTICALS, INC.;PHARMACIA & UPJOHN COMPANY |
发明人 |
WARPEHOSKI, MARTHA A.;JAGODZINSKA, BARBARA |
| 分类号 |
C12N9/99;A61K31/166;A61K38/00;A61P25/16;A61P25/28;C07C237/06;C07C237/10;C07K1/08;C07K5/06;C07K5/062;C07K7/06;(IPC1-7):C07K5/062;A61K38/05;A61K31/198 |
主分类号 |
C12N9/99 |
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