| 摘要 |
The present invention provides a heart valve prosthesis device having an occluder, an occluder base and a suture ring, where the occluder base and suture ring have a coating of anti-thrombotic/anti-fibrotic/anti-pannus material on the surface of the occluder base to approximately one-half to two-thirds to the outer peripheral edge of the suture ring, wherein the coating prevents thrombus, fibrosis and pannus from forming on the surfaces it coats. For example, the invention provides an improved heart valve prosthesis device, where the heart valve prosthesis is a mechancical heart valve, or a bioprosthetic heart valve. In addition, the invention provides an improved heart valve prosthesis where the anti-thrombotic/anti-fibrotic/anti-pannus material is polyurethane or similar material; and the invention also provides an improved suture ring for use in combination with a heart valve prosthesis device having an occluder and an occluder base, wherein the improvement comprises a coating of anti-thrombotic/anti-fibrotic/anti-pannus material on the surface of the suture ring, where the coating extends from the inner peripheral edge of the suture ring to the outer peripheral edge of the suture ring, where the coating prevents thrombus, fibrosis and pannus from originating from the surface it coats. For example, the invention provides an improved heart valve prosthesis device, where the heart valve prosthesis is a mechancical heart valve, or a bioprosthetic heart valve. In addition, the invention provides an improved heart valve prosthesis where the anti-thrombotic/anti-fibrotic/anti-pannus material is polyurethane, or similar material.
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