| 摘要 |
<p>The invention relates to 4-substituted fused heteropyrimidines and fused hetero-4-pyrimidones, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7B (PDE7B). Diseases and conditions mediated by PDE7B include osteoporosis, osteopenia and asthma. The invention also relates to processes for preparing 4-substituted fused heteropyrimidines and fused hetero-4-pyrimidones and processes for preparing compositions containing the same.</p> |
