发明名称 |
Synthesis of ceftiofur intermediate |
摘要 |
The present invention provides an improved process for the preparation of 7-amino-3-[2-(furylcarbonyl)thiomethyl]-3-cephem-4-carboxylic acid represented by formula (I) by the condensation of 7-amino cephalosporanic acid (7-ACA) represented by formula (II) with furyl-2-carbonylthiol represented by formula (III) using borontrifluoride as condensing agent in an organic solvent at a temperature range of 20°-50°C.
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申请公布号 |
US2003135041(A1) |
申请公布日期 |
2003.07.17 |
申请号 |
US20020035178 |
申请日期 |
2002.01.04 |
申请人 |
ORCHID CHEMICALS & PHARMACEUTICALS LIMITED, INDIA |
发明人 |
DESHPANDE PRAMOD NARAYAN;KHADANGALE BHAUSAHEB PANDHARINATH;KUMAR SURULICHAMY SENTHIL;DAS GAUTAM KUMAR |
分类号 |
C07D501/00;C07D501/04;C07D501/14;C07D501/36;(IPC1-7):C07D501/14 |
主分类号 |
C07D501/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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