| 摘要 |
A method and composition for destruction of infectious prion proteins associated with transmissible spongiform encephalopathy (TSE) and/or other prion protein-mediated diseases, by thermal/enzymatic treatment of the infectious prion proteins with a prion-destructive protease. The method and composition are applicable to treatment of tissue containing or contaminated with infectious prion protein strains, or disinfection or sterilization of prion-contaminated articles, such as surgical instruments, kitchen utensils, laboratory tools, etc. |
