发明名称 THE USE OF HISTAMINE H4 RECEPTOR ANTAGONIST FOR THE TREATMENT OF INFLAMMATORY RESPONSE
摘要 The present invention relates to the use of histamine H4 receptor modulators for the prevention, treatment, induction, or other disired modulation of inflammatory responses, inflammation, or diseases and/or conditions that are modulated, affected or caused by inflammation or inflammatory responses. The present invention also relates to the use of histamine H4 receptor modulators for the prevention, treatment, induction, or other disired modulation of polymorphonuclear leukocyte responses, such as migration to a particular site, or diseases and/or conditions that are modulated, affected or caused by polymorphonuclear leukocytes. The present invention also relates to the use of histamine H4 receptor modulators for the prevention, treatment, induction, or other desired modulation of mast cell responses, such as de-granulation, or diseases and/or conditions that are modulated, affected or caused by mast cells.
申请公布号 WO03057919(A2) 申请公布日期 2003.07.17
申请号 WO2002US38308 申请日期 2002.12.02
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 THURMOND, ROBIN,;SUN, SIQUAN;KARLSSON, LARS
分类号 G01N33/50;A61K45/00;A61P29/00;A61P43/00;C07K16/28;C12P21/08;C12Q1/02;C12Q1/68;G01N33/15;G01N33/566 主分类号 G01N33/50
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