| 发明名称 |
METHOD OF IDENTIFYING PROTEINS CAMs (CONSTITUTIVELY ACTIVE MUTANTS) |
| 摘要 |
The invention relates to a method of identifying protein CAMs (constitutively active mutants) wherein a library ofmutated sequences of a protein is generated, yeast cells are transformed with such a library, and the respective protein CAM is identified. Morever the invention relates to the use of such a method for identifying agonists or inverse agonists.
|
| 申请公布号 |
WO03057882(A1) |
申请公布日期 |
2003.07.17 |
| 申请号 |
WO2003EP00070 |
申请日期 |
2003.01.07 |
| 申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
FRAISSIGNES, PAULINE;GRATZER, SABINE;LEBERER, EKKEHARD |
| 分类号 |
C12N15/10;C12N15/66;G01N33/74;G01N33/76;(IPC1-7):C12N15/10 |
主分类号 |
C12N15/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
