An apparatus is provided for sealing a first layer (150) to a second layer (130), the second layer comprising one or more cavities (135) adapted to contain a pharmaceutical formulation. The apparatus comprises a roller (110) comprising a heating element (125), and a surface (1159) adapted to support the first and second layers, the surface being translatable relative to the roller. The first layer is heat sealed to the second layer when contacted by the roller to contain the pharmaceutical formulation within the one or more cavities.
申请公布号
WO03057564(A1)
申请公布日期
2003.07.17
申请号
WO2002US38922
申请日期
2002.11.20
申请人
NEKTAR THERAPEUTICS;SCHULER, CARLOS, E.;ALSTON, WILLIAM, W.;RASMUSSEN, DENNIS, R.