| 摘要 |
<p>A device and method for screening therapeutic agents for modulation of sexual stimulation, including delaying ejaculatory response, damping sexual response and increasing sexual response. The method of the present invention is particularly useful for screening candidate therapeutic agents for modulating/delaying ejaculatory response, the method comprising: (a) stimulating control subjects in a physiological region that effects sexual response with an electroejaculation probe according to a predetermined stimulating protocol; (b) determining ejaculation events in the control subjects; (c) administering to testing subjects a candidate therapeutic agent for modulating sexual stimulation; (d) stimulating the testing subjects with the electroejaculation probe according to step (a); and (e) determining the ejaculation events in testing subjects and comparing the results with the ejaculation events in the control subjects to determine the efficacy of the candidate therapeutic agent.</p> |
