发明名称 |
PSORIASIN EXPRESSION BY BREAST EPITHELIAL CELLS |
摘要 |
The invention features methods of diagnosing high grade ductal carcinoma in situ (DCIS). These methods involve measuring: (1) the level of HID-5 in a body fluid (e.g., blood or urine) of a subject suspected of having, or at risk of having, high grade DCIS; or (2) the level of HID-5 gene expression in breast tissue from a subject suspected of having, or at risk of having, high grade DCIS. The invention also embodies a method of inhibiting expression of HID-5 protein in DCIS cells and methods of treating a subject suspected of having, or at risk of having, high grade DCIS.
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申请公布号 |
CA2472163(A1) |
申请公布日期 |
2003.07.17 |
申请号 |
CA20022472163 |
申请日期 |
2002.12.30 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
POLYAK, KORNELIA;ENERBACK, CHARLOTTA |
分类号 |
G01N33/68;A61K31/7088;A61K39/395;A61K45/00;A61K48/00;A61P15/00;A61P35/00;A61P37/02;C12N5/06;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/574;(IPC1-7):C12Q1/00;A61K38/00 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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