TRIAZOLE DERIVATIVES AS CYCLOOXYGENASE (COX) INHIBITORS

摘要

A compound of the formula (I): wherein R¹ is lower alkyl which is optionally substituted with halogen, cyano, N,N-di(lower)alkylcarbamoyl, phenyl optionally substituted with halogen, or heterocyclic group, cyclo(lower)alkyl, lower alkynyl, or N,N-di(lower)alkylcarbamoyl; R² is lower alkyl, lower alkoxy, cyano, or 1H-pyrrol-1-yl; R³ is lower alkyl, lower alkoxy, or cyano; X is O, S, SO or SO₂; Y and Z are each CH or N; and m is 0 or 1; or salts thereof, which are useful as a medicament.