发明名称 |
DEGRADED AGONIST ANTIBODY |
摘要 |
The invention relates to a modified antibody which contains two or more H chain V regions and two or more L chain V regions of monoclonal antibody and can transduce a signal into cells by crosslinking a cell surface molecule(s) to thereby serve as an agonist. The modified antibody can be used as a signal transduction agonist and, therefore, useful as a preventive and/or remedy for various diseases such as cancer, inflammation, hormone disorders and blood diseases. |
申请公布号 |
EP1327681(A1) |
申请公布日期 |
2003.07.16 |
申请号 |
EP20010978852 |
申请日期 |
2001.10.22 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
FUKUSHIMA, NAOSHI;TSUCHIYA, MASAYUKI;UNO, SHINSUKE;OHTOMO, TOSHIHIKO;YABUTA, NAOHIRO;TSUNODA, HIROYUKI |
分类号 |
A61K38/00;C07K16/24;C07K16/28;C07K16/30;(IPC1-7):C12N15/09;C12N15/62;A61K39/395 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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