发明名称 DEGRADED AGONIST ANTIBODY
摘要 The invention relates to a modified antibody which contains two or more H chain V regions and two or more L chain V regions of monoclonal antibody and can transduce a signal into cells by crosslinking a cell surface molecule(s) to thereby serve as an agonist. The modified antibody can be used as a signal transduction agonist and, therefore, useful as a preventive and/or remedy for various diseases such as cancer, inflammation, hormone disorders and blood diseases.
申请公布号 EP1327681(A1) 申请公布日期 2003.07.16
申请号 EP20010978852 申请日期 2001.10.22
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 FUKUSHIMA, NAOSHI;TSUCHIYA, MASAYUKI;UNO, SHINSUKE;OHTOMO, TOSHIHIKO;YABUTA, NAOHIRO;TSUNODA, HIROYUKI
分类号 A61K38/00;C07K16/24;C07K16/28;C07K16/30;(IPC1-7):C12N15/09;C12N15/62;A61K39/395 主分类号 A61K38/00
代理机构 代理人
主权项
地址