Baccatin derivatives and a process for producing the same
摘要
<p>The object of the invention is to develop baccatin derivatives useful for preparing taxoid compounds such as paclitaxel and a process for the producing the same. The invention provides baccatin derivatives represented by the general formula (I) as well as a process for producing baccatin derivatives represented by the general formula (I) above, which comprises allowing a baccatin represented by the general formula (II) to react with a beta -ketoester in the absence of a catalyst or in the presence of a tin compound or an amine base, preferably under reduced pressure.</p>
申请公布号
EP1029857(B1)
申请公布日期
2003.07.16
申请号
EP20000102268
申请日期
2000.02.16
申请人
BIO RESEARCH CORPORATION OF YOKOHAMA;ENSUIKO SUGAR REFINING COMPANY, LIMITED;MANDAI, TADAKATSU