| 摘要 |
A coaxial-drive centrifuge provides for contactless regulation of sample temperature. The sample is contained in a multi-station chemical-processing circuit that has a metal receptor at each station. On demand, a stationary inductor induces eddy currents in the receptor as it spins by. Dissipation of the eddy current heats the receptor and the surrounding sample. The receptor has a thermal sensor that provides an optical indication of the sample temperature. A stationary contactless reader reads the optical indication. A controller activates the inductor when the reading indicates an actual temperature below a predetermined target temperature. When heating is required, the inductor is pulsed as the receptor is aligned with a gap in the inductor.The chemical-processing circuit is designed for a specific series of chemical reactions, in this case, a polymerase chain reaction (PCR) is implement as an iterated series of three steps. To this end, the chemical-processing circuit has three stations arranged in a closed loop with interconnecting channels. When a treatment is completed, the chemical-processing circuit tilts so that the sample to the next station for the next treatment. Each station has its own receptor and thermo-sensor so that each treatment can be performed at its respective optimal temperature. The centrifuge system thus provides for automating a sequence of chemical processes using contactless regulation of temperature.
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