| 发明名称 |
Pyrazole compositions useful as inhibitors of ERK |
| 摘要 |
Described herein are compounds that are useful as protein kinase inhibitors having the formula:where R1-4, Q, and T are described in the specification. The compounds are useful for treating disease states in mammals that are alleviated by a protein kinase inhibitor, particularly diseases such as cancer, inflammatory disorders, restenosis, and cardiovascular disease.
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| 申请公布号 |
US6593357(B1) |
申请公布日期 |
2003.07.15 |
| 申请号 |
US20020225719 |
申请日期 |
2002.08.22 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
GREEN JEREMY;CAO JINGRONG;HALE MICHAEL;BAKER CHRISTOPHER;MALTAIS FRANCOIS;JANETKA JAMES;MULLICAN MICHAEL;BEMIS GUY;XIE XIAOLING;STRAUB JUDITH;TANG QING |
| 分类号 |
A61B17/00;A61F2/02;A61K31/4155;A61K31/4178;A61K31/433;A61K31/437;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61K31/551;A61K45/00;A61L27/00;A61P1/00;A61P1/16;A61P1/18;A61P3/10;A61P5/00;A61P7/02;A61P9/00;A61P9/04;A61P9/10;A61P11/00;A61P13/00;A61P13/10;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P19/00;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D231/38;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D417/14;C07D471/04;(IPC1-7):A61K31/415 |
主分类号 |
A61B17/00 |
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