发明名称 |
PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS |
摘要 |
<p>A process for producing a crystalline chiral hydroxy ester of formula (1.0) is disclosed. The process comprises reacting a diol of formula (2.0), with an effective amount of isobutyric anhydride and an effective amount of a lipase enzyme in an effective amount of acetonitrile, said reaction being conducted at a low temperature, and wherein X<1> and X<2> are each independently selected from F or Cl.</p> |
申请公布号 |
HK1010563(A1) |
申请公布日期 |
2003.07.11 |
申请号 |
HK19980111788 |
申请日期 |
1998.11.06 |
申请人 |
SCHERING CORPORATION |
发明人 |
NIELSEN, CHRISTOPHER M.;SUDHAKAR, ANANTHA |
分类号 |
C21C7/10;C07C69/63;C07C69/65;C12P7/62;C12P41/00;C21C7/068;C21C7/072;(IPC1-7):C12P;C07C |
主分类号 |
C21C7/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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