CONVERSION OF RED BLOOD CELLS A, B, AND AB USING a-N-ACETYLGALACTOSAMINIDASES AND a-GALACTOSIDASE
摘要
This invention relates to enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products, and thereby converting these to non-A and non-B reactive cells. The invention further relates to using unique a-N-acetylgalactosaminidases and a-galactosidases with superior kinetic properties for removing the immunodominant monosaccharides of the blood group A and B antigens and improved performance in enzymatic conversion of red blood cells.
申请公布号
WO03027245(A3)
申请公布日期
2003.07.10
申请号
WO2002US30403
申请日期
2002.09.25
申请人
ZYMEQUEST, INC.;CLAUSEN, HENRIK;DE LA VEGA, HUMBERTO;HILL, CHERYL;LIU, QIYONG, PETER
发明人
CLAUSEN, HENRIK;DE LA VEGA, HUMBERTO;HILL, CHERYL;LIU, QIYONG, PETER