| 发明名称 |
Disruption of the glutathione S-transferase-Omega-1 gene |
| 摘要 |
The invention features non-human mammals and animal cells that contain a targeted disruption of a glutathione S-transferase-Omega-1 gene. The invention also features methods of treating an IL-1 mediated and/or inflammation mediated disorder in a mammal comprising administering an agent that inhibits GST-Omega-1 activity.
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| 申请公布号 |
US2003131370(A1) |
申请公布日期 |
2003.07.10 |
| 申请号 |
US20020298331 |
申请日期 |
2002.11.18 |
| 申请人 |
PFIZER INC. |
发明人 |
ALLEN MELANIE R.;AUDOLY LAURENT P.;GABEL CHRISTOPHER A. |
| 分类号 |
A01K67/027;A61K45/00;A61P1/00;A61P7/04;A61P7/06;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C12N5/08;C12N5/10;C12N9/10;C12N15/09;C12N15/85;C12Q1/68;(IPC1-7):A01K67/027;A61K31/00 |
主分类号 |
A01K67/027 |
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