HER2/NEU TARGET ANTIGEN AND USE OF SAME TO STIMULATE AN IMMUNE RESPONSE

摘要

A recombinant polynucleotide encoding a Her2/neu target antigen is provided, as is a recombinant Her2/neu target antigen polypeptide. Also provided are methods of using such a recombinant polynucleotide to express a Her2/neu target antigen in a cell. In addition, methods are provided for using the recombinant polynucleotide or the recombinant polypeptide to stimulate an immune response in a subject against cancer that expresses Her2/neu. Methods of making a target antigen also are provided.