The present invention relates to the identification of an oligosaccharide binding domain in the beta-subunit of AMP kinase. Methods are provided for screening for compounds that modulate oligosaccharide binding to the beta-subunit of AMP kinase. Methods of using such compound in the treatment of conditions associated with uncoupled AMP kinase activity are also provided.
申请公布号
WO03056032(A1)
申请公布日期
2003.07.10
申请号
WO2002AU01769
申请日期
2002.12.23
申请人
ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH;STAPLETON, DAVID;KEMP, BRUCE, E.