| 摘要 |
FIELD: medicine, pharmacy. SUBSTANCE: invention relates to the cyclosporine pharmaceutical composition and proposes the homogeneous, alcohol� free composition of cyclosporine that comprises cyclosporine in hydrophilic medium-carrier including propylene glycol, propylene glycol and C4-C12-fatty acids esters and polyhydroxyethylene hydrogenated castor oils being indicated components are taken in the definite following ranges of concentrations. Invention provides the improvement of biological availability of preparation and the use of these compositions is the most useful under conditions of tropic countries in relation with the absence of C1-5-alkanols, such as ethanol, that are subjected for evaporation process. EFFECT: improved and valuable medicinal properties of composition. 19 cl, 1 dwg, 2 tbl, 15 ex |
