摘要 |
<p>A process in which an N-protected heterocyclic compound such as a 1-alkoxycarbonyl-3-aminopyrrolidine is produced from a nitrogenous saturated heterocyclic compound having two kinds of nitrogen atoms, such as 3-aminopyrrolidine, by position-selectively reacting the nitrogen atom as a member of the heterocycle. A nitrogenous saturated heterocyclic compound having two kinds of nitrogen atoms is reacted with a dialkyl dicarbonate (ROCO-O-COOR) at a pH of 9 to 14 to produce a 1-alkoxycarbonyl nitrogenous saturated heterocyclic compound having a high purity.</p> |