| 摘要 |
<p>Disclosed are compositions and methods for sensitive multiplex detection of analytes. The disclosed compositions, referred to as detectors, accomplish this detection by associating specific binding molecules - which interact with desired targets - with block groups in a carrier. The block groups are made up of blocks which, through the combination of different blocks, constitute a code for a given detector. The blocks are detectable and each detector is distinguishable from other detectors by its block group. The coding of the block groups greatly increasing the number of distinguishable detectors from a relatively small number of blocks. The detection burden remains low even with such a large number of block groups because only the blocks need be distinguished from each other during detection. Numerous block molecules of each type making up the block group can be present in the carrier to effectively amplify the signal generated from targets.</p> |
