发明名称 Crystalline bis[(E)-7- [ 4-(4- fluorophenyl)- 6-isopropyl-2- [methyl (methylsulfonyl] amino] pyrimidin -5-yl] (3R,5S)-3, 5-dihydroxyhept -6-enoic acid]calcium salt
摘要 The present invention relates to a crystalline form of the compound bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl (methylsulfonyl) amino] pyrimidin-5-yl] (3R, 5S)-3, 5-dihydroxyhept-6-enoic acid]calcium salt, as well as processes for its manufacture and pharmaceutical compositions comprising the crystalline form, which is useful as an agent for treating hyperlipidemia, hypercholesterolemia and atherosclerosis.
申请公布号 AU762909(B2) 申请公布日期 2003.07.10
申请号 AU20000018826 申请日期 1999.12.23
申请人 ASTRAZENECA AB 发明人 NIGEL PHILLIP TAYLOR
分类号 A61K31/505;A61P3/06;A61P9/00;A61P9/10;A61P43/00;C07D239/42;(IPC1-7):C07D239/42 主分类号 A61K31/505
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