发明名称 1-(Adamantyl) amidines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
摘要 Use of a compound of the formula (1), wherein X is an alkylene chain comprising 0, 1, 2, 3 or 4 carbon atoms; R1, R2 and R3 are independently selected from hydrogen, alkyl and aryl; R4, R5 and R6 are independently selected from hydrogen, alkyl, aryl, halogen and alkoxy; and prodrugs thereof and pharmaceutically acceptable salts thereof; in the manufacture of a medicament for use in the treatment of a condition generally associated with abnormalities in glutamatergic transmission.
申请公布号 US2003130354(A1) 申请公布日期 2003.07.10
申请号 US20020291413 申请日期 2002.11.12
申请人 VERNALIS RESEARCH LIMITED 发明人 GILLESPIE ROGER JOHN;SNAPE MICHAEL FREDERICK;WARD SIMON EDWARD
分类号 A61P25/00;A61K31/155;A61P25/28;A61P43/00;C07C257/14;C07C257/16;(IPC1-7):A61K31/155 主分类号 A61P25/00
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