发明名称 |
TECHNIQUE AND SCREENING METHOD FOR DETECTING REVERSIBLE PROTEIN-PROTEIN INTERACTIONS |
摘要 |
The invention relates to methods and assays for detecting protein-protein interactions and for testing active substances in expression systems such as cells. According to the invention, protein I interacts with protein II, and a transfer of protein I into a cell compartment ensues, in which both protein I as well as protein II do not normally occur. When detecting protein II in the compartment, into which protein I was transferred, an interaction between protein I and protein II is determined. |
申请公布号 |
WO02052272(A3) |
申请公布日期 |
2003.07.10 |
申请号 |
WO2001EP15265 |
申请日期 |
2001.12.21 |
申请人 |
EVOTEC OAI AG;MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.;ROCKS, OLIVER;WITTINGHOFER, ALFRED |
发明人 |
ROCKS, OLIVER;WITTINGHOFER, ALFRED |
分类号 |
C40B30/04;G01N33/68 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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