Sorting and counting of biological particles, comprises marking with paramagnetic or dielectric nanoparticles, to be passed a sensor which registers field changes to give signals which can be counted electronically

摘要

Sorting and counting biological particles, where the non-agglutinate particles are marked with paramagnetic or dielectric nano particles of 5-500 nm. The marking is through bi-functional molecules, genetic probes, viruses or specific adsorbent proteins, and the marked biological particles are boosted in an electrical or magnetic field before or after counting. Sorting and counting biological particles, where the non-agglutinate particles are marked with paramagnetic or dielectric nano particles of 5-500 nm. The marking is through bi-functional molecules, genetic probes, viruses or specific adsorbent proteins, and the marked biological particles are boosted in an electrical or magnetic field before or after counting. The biological particles are carried by a shrouding liquid continuously or separately as a string of pearls past a sensor (46), which can be capacitative or magnetic e.g. gradiometeric, magnetoresistive or flux-gate. The sensor is a component part of a micro-electromechanical system (40) with micro-fluid elements of 5-500 mum. The field changes registered as the marked particles flow past are converted into signals which can be counted electronically.