| 摘要 |
<p>The invention relates to mutated penicillin acylases having a high synthesis/hydrolysis ratio in comparison with wild-type penicillin acylases and at least 1% of the activity. The invention also relates to a process for the enzymatic preparation of a ß-lactam antibiotic from a ß-lactam nucleus and an activated side chain with the aid of mutated penicillin acylases.</p> |
