| 发明名称 |
Bicyclic androgen and progesterone receptor modulator compounds and methods |
| 摘要 |
The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR and PR. More particularly, the invention relates to nonsteroidal compounds and compositions that are high affinity, high specificity agonists, partial agonists (i.e., partial activators and/or tissue-specific activators) and antagonists for AR and PR. Also provided are methods of making such compounds and pharmaceutical compositions, as well as critical intermediates used in their synthesis.
|
| 申请公布号 |
US2003130505(A1) |
申请公布日期 |
2003.07.10 |
| 申请号 |
US20020299909 |
申请日期 |
2002.11.18 |
| 申请人 |
ZHI LIN;TEGLEY CHRISTOPHER;PIO BARBARA;VAN OERVEREN CORNELIS ARJAN;MOTAMEDI MEHRNOUCH;MARTINBOROUGH ESTHER;WEST SARAH;HIGUCHI ROBERT;HAMANN LAWRENCE G.;FARMER LUC |
发明人 |
ZHI LIN;TEGLEY CHRISTOPHER;PIO BARBARA;VAN OERVEREN CORNELIS ARJAN;MOTAMEDI MEHRNOUCH;MARTINBOROUGH ESTHER;WEST SARAH;HIGUCHI ROBERT;HAMANN LAWRENCE G.;FARMER LUC |
| 分类号 |
A61K31/37;A61K31/4025;A61K31/404;A61K31/407;A61K31/416;A61K31/4178;A61K31/428;A61K31/47;A61K31/4704;A61K31/4709;A61K31/4725;A61K31/496;A61K31/517;A61K31/536;A61K31/5377;A61K31/538;A61K31/55;A61P5/26;A61P5/28;A61P5/34;A61P5/36;A61P7/04;A61P7/06;A61P13/08;A61P15/00;A61P15/04;A61P15/08;A61P15/10;A61P15/16;A61P15/18;A61P17/10;A61P17/14;A61P35/00;A61P43/00;C07D209/34;C07D209/96;C07D215/22;C07D215/227;C07D215/36;C07D215/38;C07D215/48;C07D239/80;C07D265/18;C07D265/36;C07D277/68;C07D311/14;C07D311/20;C07D401/04;C07D401/12;C07D405/04;C07D405/12;C07D409/04;C07D409/12;C07D413/04;C07D417/04;(IPC1-7):A61K31/551;A61K31/470;A61K31/366 |
主分类号 |
A61K31/37 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
